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Table 3 Comparative analysis of some M. tuberculosis CDC1551 strain PE and PE_PGRS proteins with their H37Ra, H37Rv and BCG Pasteur strain orthologes

From: Bioinformatic identification of Mycobacterium tuberculosis proteins likely to target host cell mitochondria: virulence factors?

  CDC 1551 H37Ra H3TRv BCG Pasterur 1173P2
  MT_0118 MRA_0115 Rv0109 BCG_0142
Putative identity PE–PGRS family protein
% Similarity   81.4 81.4 81.4
MITOPROT II
Score 0.9796 0.1144 0.9799 0.1144
PSORT II Score 82.6% 11.1% 82.6% 11.1%
Signal P Score 0.988 0.999 0.998 0.999
  MT_0349 MRA_0344 Rv0335c BCG_0374
Putative identity PE family protein
% Similarity   81.9% 81.9% 81.3%
MITOPROT II     
Score 0.9902 0.0157 0.9746 0.0155
PSORT II Score 73.9% 17.4% 69.6% 21.7%
Signal P Score 0.640 NS NS NS
  MT_0854 MRA_0841 Rv0832 BCG_0885
Putative identity PE–PGRS family protein
% Similarity   56.2% 56.2% 56.2%
MITOPROT II
Score 0.9326 0.4901 0.5935 0.5738
PSORT II Score 73.9% 4.3% 8.7% 11.1%
Signal P Score 0.999 0.998 0.993 0.998
  MT_1886 MRA_1830 Rv1818c BCG_1853c
Putative identity PE–PGRS Family
% Similarity   53.4% 53.4% 53.4%
MITOPROT II
Score 0.9983 0.1494 0.1494 0.1475
PSORT II Score 73.9% 13.0% 13.0% 13.0%
Signal P Score 0.974 0.991 0.991 0.991
  MT_2690 MRA_2643 Rv2615c BCG_1035c
Putative identity PE–PGRS Family
% Similarity   79.0% 79.0% 78.2%
MITOPROT II
Score 0.9472 0.9472 0.8178 0.9488
PSORT II Score 52.2% 52.2% 13.0% 52.2%
Signal P Score 0.917 0.917 0.849 0.917
NS non signal