Kolmogorov-Smirnov test for discrete distributions of Genic-TSSRs on a chromosome. A two-sided Kolmogorov-Smirnov test (KS-test) comparing the average percentage of counts of each translation stop signals among 400 genes from Escherichia coli K12 based on assigning these genes to three categories. (A) genes are assigned based on the location on each replichore (Left (∆) vs. Right (▼)); (B) genes are assigned based on their orientation on the leading or lagging stands of the DNA (Forward (■) vs. Reverse (□)), or (C) genes are assigned based on their proximity to the replication origin or terminus (Ori (●) vs. Ter (○)). The insert shows the standard deviation of the average percentage of counts of all nine types of translation stop signals in each gene assignment.