Skip to main content

Advertisement

Figure 5 | Microbial Informatics and Experimentation

Figure 5

From: Mycobacterium tuberculosis and Clostridium difficille interactomes: demonstration of rapid development of computational system for bacterial interactome prediction

Figure 5

Number of novel interactions at different levels of precision. (A) Observed number of novel predictions in the Mtb interactome uncovered at varying level of estimated precisions. For example, at 90% precision, the algorithm uncovers 786 novel interactions and 1,068 known interactions; at expected 80% precision it uncovers 1,595 novel interactions and 1,488 known interactions. The threshold on the random forest output that corresponds to each of the precisions shown in the figure: 0.88 (90% precision), 0.79 (80%), 0.67 (70%) and 0.49 (60%).(B) Observed number of novel predictions in the CD interactome uncovered at varying level of estimated precisions. For example, at 90% precision, the algorithm uncovers 143 novel interactions and 812 known interactions; at expected 80% precision it uncovers 580 novel interactions and 1,587 known interactions. The threshold on the random forest output that corresponds to each of the precisions shown in the figure: 0.98 (90% precision), 0.86 (80%), 0.66 (70%) and 0.58 (60%).

Back to article page