L4 Environmental Metabolome. In the figure, edges represent enzyme functions identified in annotated metagenomes. Nodes are predicted metabolites, inferred by the reactions catalyzed by detected enzyme functions. Nodes are highlighted if calculated PRMT scores for seasonal metagenomes correlate strongly (i.e. in the top or bottom 5th percentile of randomized resamples) with relative abundance of measured environmental parameters (Red for Total Organic Carbon, blue for Total Organic Nitrogen, and gold for Soluble Reactive Phosphorus). Edges are highlighted in one of 23 colors if they connect nodes that correlate with relative abundance of a bacterial phylum.