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Table 7 GO biological processes assignments.

From: Stringent response of Escherichia coli: revisiting the bibliome using literature mining

Gene Ontology concepts

Frequency of Ontology Annotation

Brief Description

Gene Products

Coding Genes

   

Name

Frequency of Assignment

Frequency of Annotation

Name

Frequency of Annotation

GO:0008152 Metabolic process

89%

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances.

RelA

80%

79%

relA

72%

   

LacZ

10%

24%

lacZ

26%

GO:0015949 Nucleobase, nucleoside and nucleotide interconversion

80%

The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide is synthesized from another nucleobase, nucleoside or nucleotide.

RelA

80%

79%

relA

72%

   

SpoT

20%

31%

spoT

46%

GO:0015969 Guanosine tetraphosphate metabolic process

80%

The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.

RelA

80%

79%

relA

72%

   

SpoT

20%

31%

spoT

46%

GO:0006350 Transcription

56%

The synthesis of either RNA on a template of DNA or DNA on a template of RNA.

RpoS

16%

22%

rpoS

17%

   

CRP

12%

6%

crp

4%

   

RpoB

10%

18%

rpoB

16%

   

Mfd

10%

2%

mfd

2%

GO:0006355 Regulation of transcription, DNA-dependent

52%

Any process that modulates the frequency, rate or extent of DNA-dependent transcription.

RpoS

20%

22%

rpoS

17%

   

CRP

14%

6%

crp

4%

   

Mfd

12%

2%

mfd

2%

GO:0006412 Translation

40%

The cellular metabolic process by which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain.

RplK

28%

7%

rplK

6%

   

DksA

28%

8%

dksA

3%

   

EF-Tu

13%

14%

tufB

3%

GO:0006950 Response to stress

39%

A change in state or activity of a cell or an organism as a result of a disturbance in cellular homeostasis, usually, but not necessarily, exogenous.

RecA

20%

16%

recA

20%

   

RelB

16%

4%

relB

3%

   

NusA

10%

5%

nusA

4%

GO:0042594 Response to starvation

39%

A change in state or activity of a cell or an organism as a result of a starvation stimulus, deprivation of nourishment.

SpoT

67%

31%

spoT

46%

   

DksA

30%

8%

dksA

3%

GO:0006970 Response to osmotic stress

38%

A change in state or activity of a cell or an organism as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.

RpoS

59%

22%

rpoS

17%

   

EF-Tu

34%

14%

tufB

3%

GO:0005975 Carbohydrate metabolic process

36%

The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

LacZ

94%

24%

lacZ

26%

GO:0006974 Response to DNA damage stimulus

36%

A change in state or activity of a cell or an organism as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

Mfd

28%

2%

mfd

2%

   

RecA

11%

16%

recA

20%

   

RecG

11%

3%

recG

NA

GO:0006281 DNA repair

36%

The process of restoring DNA after damage that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

Mfd

28%

2%

mfd

2%

   

RecA

11%

16%

recA

20%

   

RecG

11%

3%

recG

NA

  1. GO terms were assigned to annotated concepts associated with gene products annotations. A threshold of 35% of documents was considered for ontology assignment and a threshold of 10% was used to point out the gene products that most contributed to such assignment.
  2. NA: corresponds to non-annotated genes in the corpus.